neoformans in Mind microvascular endothelial cells (BMECs) calls for protein kinase C-alpha activation. The CPS1 gene is needed for C. neoformans adherence to your surface protein CD44 of human BMECs [15]. The dissemination of pathogen in to the Mind is controlled by Isc1 gene encoding an enzyme that hydrolyzes inositol. Just lately, Huang et al. [
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